Ironically, if Williams does win on Saturday, she will be displacing a record already belonging to the family - to her biggest competitor, to her biggest inspiration.
The women's doubles final is after that, featuring the second-seeded pairing of Ekaterina Makarova and Elena Vesnina taking on the ninth-seeded Hao-Ching Chan and Monica Niculescu.
At 37 years and 28 days, Williams is looking for her first grand slam title since Wimbledon nine years ago, when she claimed her fifth crown here and seventh in total.
Then just earlier this week, a reporter made another blunder at a press conference following Murray's defeat by United States player Querrey.
When Martinez won at Wimbledon for her only major, she beat 37-year-old Martina Navratilova in the final.
Federer will be facing Marin Cilic for his 19th Grand Slam in his 11th Wimbledon Finals appearance. "A final is a final", Muguruza said. "I would love you to!". "So those are definitely similarities". She reached the Wimbledon semifinals last year, and the Australian Open final this year. Poverty, racism, the death of a beloved sister in a shooting, the diagnosis of an autoimmune illness in 2011, the effects of which she lives with every day and, coming into this tournament, what turned out to be false allegations of causing a fatal traffic accident.
Williams was involved in a fatal auto crash June 9 near her home in Palm Beach Gardens, Fla. Barson's vehicle ran into the side of Williams' SUV, and Jerome Barson, 78, a passenger in his wife's auto, sustained major injuries. In the video, Williams appeared to slow to avoid a auto making a left turn in front of her, then proceeded through the intersection when her vehicle was struck.
"There are really no words to describe, like, how devastating and - yeah".
"I think it's wonderful to have the opportunity to play well and to be strong and have experience", Williams said.
But she has bounced back, playing some of her best tennis over the past 12 months. She is 7-8 lifetime in her previous 15 major finals. "We work so many years for these moments that she has right now, and I'm really happy for her", the 23-time grand slam victor told Yahoo Sports.
"For me, it's incredible".
"I don't think about my age", Williams told BBC Sport.
Muguruza, 23, is no pushover.
Both play an aggressive game, with Muguruza not only possesses a big forehand and a back-hand down the line, but she showed in her match against Magdalena Rybarikova that she still had a lot of speed and agility up at the net.
Muguruza is the first Spanish woman to reach more than one Wimbledon final since Arantxa Sanchez Vicario, who lost twice in the 1990s.
"Serena did play her in a final".
In 2003, with the Venus-Serena combine truly reigning over the women's game, the elder sister had her first serious injury (abdomen) - she dropped outside the top-ten for the first time since 1997. I did think of that, and I tried to do the things she would do. Is very different to hold the trophy than to have - you know...
If Williams is slowing down to savor the moments, she isn't saying so. "I definitely will ask her (for help)", Venus added.
Williams arrived in England a few weeks after being involved in a two-car accident in Florida; not long afterward, a passenger in the other vehicle died. I have one more match that I'd like to, you know, be the victor of. I'll want to try to continue to play like I have in all these matches that I've played so far. "But there's still more to happen".
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