Iran is one of the largest members of the OPEC oil cartel and previous political protests in the country have had a major affect on worldwide oil prices. And yet tens of thousands of people have protested across the country since Thursday.
Online messaging and photo sharing platforms Telegram and Instagram remained blocked on mobile phones, having been interrupted soon after protests began. The city is considered holy among world's Shiite Muslims as Reza, the 8th Shiite imam, is buried here.
The protests on Tuesday entered on its sixth day.
The violence overnight brings the unofficial total to at least 22 dead since the demonstrations - which started out as rallies against high inflation for basic food products and other economic woes - began in Iran's second-largest city, Mashhad.
Demonstrators are angry over corruption and economic hardship in a country where youth unemployment reached 28.8 per cent past year.
Several conservatives depicted the protests as an uprising against "oppression and tyranny", in the words of Senator Rob Portman.
Aslam predicted foreign influence, such as the support expressed for demonstrators by fierce regional rival Israel, tweets by Trump and the comments from Johnson only create more instability in the country. "They have nothing to be happy about", said Sarita Mohammadi, a 35-year-old teacher in Tehran.
Is theocracy the reason behind protests?
Reviving sanctions on Iran's main export would allow Tehran to argue that the United States is ultimately the cause of Iran's economic problems, said Richard Nephew, who worked on sanctionspolicy at the White House under president Barack Obama. For the next eight years limited anti-government activities continued. After a cut, demonstrators are seen coming to the aid of another protester, who appears seriously wounded.
Political protests are rare in Iran, where security services are pervasive.
It is feared that the protests and reaction of the regime could become even more violent in the days to come.
That was in sharp contrast to President Obama's strong vocal support for pro-democracy protesters in Egypt in 2011 during the so-called Arab Spring.
In Najafabad, a city in the central province of Isfahan, a rioter opened fire to police forces on Monday night, killing one and injuring three others with a hunting rifle.
After almost a week of rare protests in Iran, it is clear momentum is building.
A total of 21 people have died in the unrest as protesters in some areas attacked government buildings and police stations.
In 2009, authorities ruthlessly put down protests against the re-election of hardliner Mahmoud Ahmadinejad.
The protesters denounce both Rouhani's reformers and the hard-liners led by Supreme Leader Ali Khamenei. The time for Iran was, however, more hard in 2009 as protests coincided with Arab revolts in the region.
The US stance to the unrest, which has included a string of tweets from President Donald Trump, has drawn an angry response from the Iranian leadership.
"The people of Iran are finally acting against the brutal and corrupt Iranian regime", he posted Tuesday.
It is still premature to predict the outcome of the protests.
In addition, most foreign journalists are barred from the country and the Iran government has shut down some social media channels inside the country.
How has the government responded? "The government has been taken by surprise and the security forces have been slow to act". The government has arrested dozens of activists on charges including "harsh chanting", and to the internet, and particularly social media.
He has taken to Twitter multiple times since the protests erupted last week.
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