Targets include the head of the Iran judiciary, Sadegh Amoli Larijani, and a Chinese ceramics company called BOCHUANG CERAMIC, INC.
Also on Friday, the United States imposed separate sanctions against 14 Iranian individuals and entities it accuses of rights abuses, censorship and support for weapons proliferators.
In a background briefing, senior administration officials said this is Trump's "waiver" on Iran.
Iran has said it's not interested in any renegotiation and would nearly certainly view a side agreement between the USA and Europe as a violation of the deal.
If Iran does not comply with any of these provisions, American nuclear sanctions would automatically resume.
"Our worst expectations are coming true", Ryabkov said Saturday.
Iran promised a strong reaction to the sanctions, which it said violate global law and prior United States commitments. "We have sanctioned almost 100 individuals and entities involved with the Iranian regime's ballistic missile program and its other illicit activities". The two sides exchanged opinions on a statement regarding the Iran nuclear deal made by the US, Xinhua news agency reported.
The British and German foreign ministries said they had taken note of the decision and would confer with France before deciding on a course of action.
The officials said Trump expected America's European allies who are also parties to the 2015 accord, which swapped sanctions relief for a rollback of Iran's nuclear program, to join with him in reworking the deal. JCPOA (the nuclear deal) is not renegotiable: "rather than repeating exhausted rhetoric, United States must bring itself into full compliance - just like Iran", Zarif also wrote on his Twitter account.
"In what we heard yesterday, I don't see any invitation for Iran to enter dialogue", he said.
Iran, despite repeatedly claiming its nuclear programme is only for peaceful purposes, has vowed to "shred" the deal if Washington pulls out.
The Iranian president further hailed the deal as "a long-lasting victory for Iran". The 2015 agreement between the United States and Iran also was signed by China, France, Russia, Britain, Germany and the European Union, and these countries would have been unlikely to join the United States in reimposing sanctions. It now expires after a decade.
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