Thompson scored 52 points - the third 50-point game in the league this year - shot only 29 times and made an NBA-record 14 threes in just three quarters.
The game was out of reach by halftime, with the Golden State Warriors notching 92 points in the first half, the second most in National Basketball Association history.
Thompson entered Monday night's game at the United Center in Chicago on a relative cold streak.
And the Warriors witnessed Thompson do this after spending the first seven regular-season games averaging 15.1 points while shooting a combined 44-of-111 from the field (39.6 percent) and 5-of-36 from 3-point range (13.9 percent). His contract comes to an end next season and it is quite possible that he will consider free agency as it is quite possible that he ends up getting a lot more money on his new contract.
Arguably the most entertaining game of the season, the Golden State Warriors will have to find a way to keep that energy on the road following an electric home victory.
Thompson later revealed Curry had urged him to go for his record as he continued to drain a series of three-pointers.
D'Angelo Russell scored 25 points and Caris LeVert had 23 for the Nets, who made 20 three-pointers in 42 attempts and cut a 19-point deficit down to two.
What Klay Thompson did to Chicago is not fair - but so much fun to watch.
On a night when Klay was hot, Curry played the second fiddle but affected the game in multiple dimensions.
Ersan Ilyasova led the scoring with 19 points while Malcolm Brogdon and Eric Bledsoe both had 17 points apiece. The Warriors set a handful of records for Bulls opponents in a 149-124 haymaker. He added eight rebounds, five assists and three steals. Luka Doncic scored 22 points, and Wesley Matthews had 21. Thompson broke the NBA's single-game record for 3-pointers. But on the floor where he scored a career-best 54 points in 2013, his performance seemed nearly quiet because of Durant.
Zach LaVine had 20 points on 6-of-16 shooting for the Bulls.
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